Fam 2020

Current Status of Trial
Completed
Study Aim
Treatment MCI
Study Design
RCT
Blinding
Unclear
Intervention type
Non-pharmacological
Intervention
Mindfulness
Dosage and Duration
Forty-seven participants with MCI were randomized into two groups: a mindfulness practice group and a control group. Functional magnetic resonance imaging of the brain and neurocognitive tests were performed before and after the 3-month intervention.
Absolute Number of Participants
47
Health Status/Diagnosis
Mild Cognitive Impairment (MCI)
Key Points
"Participants in the mindfulness group had significantly better temporal global efficiency than controls after 3-months of intervention. Localized changes of temporal nodal properties were present in the right cingulate gyrus, insula, and left superior temporal gyrus. Together, these results suggest greater information transmission efficiency at both the global and local spatiotemporal level. In terms of cognitive function, verbal recognition memory improved in the mindfulness group compared to the controls. Conclusion Elders who practiced mindfulness had better brain network efficiency and neurocognitive function relative to controls in this study, suggesting that mindfulness may be of benefit to aging adults with early cognitive degeneration." Fam 2020