Matsubara 2021

Current Status of Trial
Completed
Study Aim
Treatment MCI
Study Design
RCT
Blinding
No blinding
Intervention type
Non-pharmacological
Intervention
Oral health intervention by dental hygienists
Dosage and Duration
Fifty-five community-dwelling older adults with a Mini-Mental State Examination score of ≥21 to ≤26 who had not visited a dental clinic in the previous year were randomized to an intervention group (n = 28) or a control group (n = 29). The intervention group received monthly oral health intervention by dental hygienists for 8 months while the control group did not.
Absolute Number of Participants
55
Health Status/Diagnosis
Mild Cognitive Impairment (MCI)
Unit of Allocation and/or Setting
Community setting
Primary outcomes
Cognitive functions
Key Points
"twenty-five subjects in the intervention group (mean age 77.0 years) and 25 in the control group (mean age 72.8 years) completed the study. Significant improvements were observed in the Trail Making Test (TMT)-A, TMT-B, bleeding on probing rate, oral diadochokinesis, tongue pressure and chewing ability in the intervention group (P < 0.05). There were also significant interactions between the TMT-A and TMT-B scores, oral diadochokinesis, tongue pressure and chewing ability (P < 0.05)." Matsubara 2021