Mozolic 2010

Current Status of Trial
Study Aim
Cognitive Enhancement (healthy)
Study Design
Intervention type
Training Program//Educational Control Program
Dosage and Duration
Individualized attention training program that is targeting auditory and visual attention. All task stimuli and distractor were presented to participants on a movie screen and overhead speakers via an LCD projector the responses on each task were made by giving verbal or handwritten answers over 8 weeks
Absolute Number of Participants
Health Status/Diagnosis
Healthy Elderly
Main Diagnostic Criteria
Corrected visual acuity of 20/40 or better in both eyes//Normal colour vision//No hearing loss no greater than 50 dB at 1000 and 2000 Hz//No evidence of dementia or cognitive impairment (Mini-Mental Status Exam score within 2.5 standard deviations of the mean for their age and education level)//No evidence of current substance abuse, indicated by a score below 10 on the Alcohol Use Disorders Identifaction Test //No history of a brain surgery
Co-morbid Health Condition/Other Participant Characteristics
Aged 65 to 75 years
Country or Countries of Recruitment
United States (USA)
Unit of Allocation and/or Setting
Community setting
Study start date
Primary outcomes
MRI Images//Cerebral Blood Perfusion
Key Points
Training program produced significantly larger increases in resting cerebral blood flow to the prefrontal cortex in comparison with the control program