Ten 2019

Current Status of Trial
Completed
Study Aim
Cognitive Enhancement (healthy)
Study Design
RCT
Blinding
Unclear
Intervention type
Non-pharmacological
Intervention
Computerized cognitive training
Dosage and Duration
An 8-week proof-of-concept randomized controlled trial to investigate the effect of a commercial CCT intervention, alone and when preceded by exercise, on cognitive function. Participants (124; aged 65-85 years) performed 8-weeks of: 1) Group-based CCT (Fit Brains®) 3x/week for 1 hour plus 3x/week home-based training; 2) Group-based CCT preceded by exercise (Ex-CCT) 3x/week for 1 hour plus 3x/week home-based training (exercise+CCT); or 3) Group-based balanced and toned (BAT) classes 3x/week for 1 hour (control).
Absolute Number of Participants
124
Health Status/Diagnosis
Healthy Elderly
Co-morbid Health Condition/Other Participant Characteristics
Aged 65 to 85 years
Primary outcomes
Cognition: memory (Rey Auditory Verbal Learning Test) // Cognition: executive function (Stroop Test; Trail Making Tests; Flanker Test; Dimensional Change Card Sort Test)
Key Points
"At trial completion, there were no significant between-group differences in memory (p > .05). However, compared with BAT, CCT and Ex-CCT significantly improved Stroop performance (-10.72, 95% CI [-16.53,-4.91]; -7.95, 95% CI [-13.77,-2.13], respectively). Moreover, Ex-CCT significant improved performance on TMT (-13.65, 95% CI [-26.09,-1.22]), the Flanker Test (6.72, 95% CI [2.55,10.88]), and the DCCS Test (6.75, 95% CI [6.75, 95% CI [0.99,12.50]). CONCLUSION: An 8-week CCT program may promote executive functions in older adults and combining it with a bout of exercise may provide broader benefits." Ten 2019